Allergies

Mast cells can be directed towards anything: dust, pollen and even people.
Unfortunately they can't react towards the last: people whom your subconscious and conscious have meticulously dissected and deemed molecularly unacceptable to your very being.

We really can't deal with those whom we can't seem to set our eyes upon let alone waste any other sensory modality. The point is being that their existence has became your bane. It is really not your fault if they turn out to have manners of a five-year old, behaviours rivaling the Teletubbies, neonatal nuances and mindsets of the sixties.

Arcane irritants.
Choking characters.
Toxic personalities.

However life is not that kind to spare you from the balance. We resort to dealing with people we rather not deal with due to so many reasons.

The only way to keep your peace of mind then is to be as clinical as possible in those dealings. By that I mean: keeping things black and white and not involving any gray as the last spells trouble. Two plus two equals four and no lingering around for any small talk.

Sensory isolation helps me keep my sanity and my peace of mind.
A big word it has become these days.